Abstract TP199: Impact Of Dementia On In-hospital Outcomes Among Patients Admitted For Acute Stroke: Insights From The National Inpatient Sample Database

Introduction: Impact of Dementia on hospitalization metrics in acute stroke patients has not been thoroughly investigated. Methods: This cross-sectional analysis used the NIS database from 2018-2020. ICD-10-CM codes defined acute stroke as primary diagnosis and dementia as secondary diagnosis. Outcomes included in-hospital mortality, length of stay (LOS), inflation-adjusted total charges, and non-home discharges. Statistical models on R Statistical Language (v4.5.0) were used to depict associations between dementia and each outcome. In patients with dementia, we also evaluated the impact of stroke subtype [ischemic stroke (IS), intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH)] on outcomes. Results: Between 2018-2020, 1,899,015 acute stroke hospitalizations were identified; out of which 220,575 (11.6%) had coexisting dementia. When stratified by stroke type, IS (87%) was most common, followed by ICH (11%), and SAH (1.8%). Compared to stroke without dementia, former had lower odds of in-hospital mortality (OR = 0.83, 95% CI: 0.79–0.87, p