Abstract TP241: Redefining Ischemic Core, Penumbra, and Target Mismatch on CT Perfusion in Acute Anterior Distal Medium Vessel Occlusions

Stroke 2026

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Authors: Dhairya A. Lakhani, Cynthia Greene, Hamza Salim, Argye Elizabeth Hillis, Kambiz Nael, Jeremy Josef Heit, Tobias Djamsched Faizy, Vivek Srikar Yedavalli
DOI: 10.1161/str.57.suppl_1.tp241
Cited by: 0

Abstract

Background: Recent trials of endovascular thrombectomy (EVT) for acute distal medium vessel occlusions (DMVOs) were negative but also used inconsistent imaging-based inclusion criteria, whereas many successful large vessel occlusion (LVO) EVT trials used empirically validated CT perfusion-based target mismatch (TMM) criteria: an ischemic penumbra (time-to-maximum [Tmax] >6s) to core (relative cerebral blood flow [rCBF] 6s to rCBF 8s and rCBF 8s to rCBF

Fields of Study & Subjects

Acute Ischemic Stroke Management Intracranial Aneurysms: Treatment and Complications Cerebrovascular and Carotid Artery Diseases

Publication details

Journal / source
Stroke
Volume
57
Issue
Suppl_1
Publication date
29 January 2026
Language
EN