Abstract TP345: NAD/NADP Dynamics After Stroke: Preliminary Evidence Linking Metabolism to Recovery

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Authors: Melba Zúniga Gutiérrez, jennifer Huang, Jeng Shi Kong, Daniela Mercado Pena, Maria Cedeno-Bruzual, Andriy Yabluchanskiy, Camila Bonin Pinto, Faddi Ghassan Saleh Vélez
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Abstract

Background: Nicotinamide adenine dinucleotide (NAD) and its phosphorylated form NADP are essential coenzymes in redox metabolism and cellular repair. Their depletion has been implicated in aging, mitochondrial dysfunction, and poor neurovascular recovery post-stroke. However, little is known about NAD/NADP levels during early stroke recovery or their relationship to functional outcomes. Methods: Acute stroke patients were enrolled at OU Medical Center and underwent serial assessments at

Fields of Study & Subjects

Stroke Rehabilitation and Recovery Sirtuins and Resveratrol in Medicine Neurological Disorders and Treatments

Publication details

Journal / source
Stroke
Volume
57
Issue
Suppl_1
Publication date
29 January 2026
Language
EN