Abstract WP369: Triglyceride-Glucose Index; a Novel Predictor of Stroke and Cardiovascular Events in Patients with Myocardial Infarction: a Systematic Review and Meta-analysis

Background: The Triglyceride-Glucose (TyG) index has recently come under study as a reliable, inexpensive marker of insulin resistance. It is garnering attention as a potential tool for prognostication in cardiovascular disease. It’s utility in the specific circumstance of patients with Myocardial infarction (MI), however, is yet to be established. This meta-analysis aimed to assess the association between the TyG index and cerebrovascular events in patients with MI. Methods: A meta-analysis of studies evaluating the TyG index with MI was conducted using the electronic databases PubMed, Embase, and Google Scholar. Events with values reporting elevation of the TyG index; the 3rd quartile vs the 1st quartile were taken. Forest plots summarizing odds ratios (OR) with 95% confidence intervals (CIs) were analyzed for the primary outcome of stroke and secondary outcomes including Major Adverse Cardiovascular Events (MACE), recurrent Myocardial Infarction (MI), revascularization, and re-hospitalization. A p-value of