Small noncoding RNA TY2 enhances efferocytosis and improves outcomes in a mouse model of sepsis

JCI Insight 2026 Open access

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Authors: Alessandra Ciullo, Xaviar Michael Jones, Hiroaki Komuro, L. Li, Anh Nguyen, Eduardo Marbán, Ahmed Gamal-Eldin Ibrahim
DOI: 10.1172/jci.insight.196153
Cited by: 0
References: 7

Abstract

TY2 is a drug based on a natural compound with potent anti-inflammatory effects. TY2 improved outcomes in mice with severe bacterial infection.

Fields of Study & Subjects

Phagocytosis and Immune Regulation Sepsis Diagnosis and Treatment Immune Response and Inflammation

Publication details

Journal / source
JCI Insight
Volume
11
Issue
5
Publication date
22 January 2026
Language
EN