Cardiovascular complications of pregnancy
Abstract
The maternal cardiovascular system undergoes dramatic remodeling in response to the stresses of pregnancy. Although in most cases these changes are temporary and well tolerated, in others they can give rise to complications, including cardiomyopathy, coronary artery disease, and hypertensive cardiovascular disease. Despite an increasing number of preclinical models to study these diseases, specific treatments for any of these pregnancy complications are lacking. As the maternal mortality rate is rising in the United States, it is critical to understand the molecular mechanisms driving cardiovascular changes during pregnancy, and the pathology that can result.
Fields of Study & Subjects
Cardiovascular Issues in Pregnancy
Pregnancy and preeclampsia studies
Cardiac Imaging and Diagnostics
Publication details
- Journal / source
- Journal of Clinical Investigation
- Publisher
- American Society for Clinical Investigation
- Volume
- 136
- Issue
- 1
- Publication date
- 1 January 2026
- Language
- EN