Polyendocrine metabolic ovarian syndrome (PMOS)/polycystic ovary syndrome (PCOS): current and future trends
Abstract
Polycystic ovary syndrome (PCOS), also known as polyendocrine metabolic ovarian syndrome (PMOS), is the most common endocrinologic disorder to affect women. Despite this, the pathophysiology of the disease is not entirely known. This has hindered the diagnosis of the disease and appropriate treatment for millions of individuals. In this Review, we discuss the proposed pathophysiology of PCOS from a translational perspective. We review the existing diagnostic criteria of PCOS and current management strategies. Finally, we discuss the long-term health sequelae associated with PCOS, future directions, and areas of needed research in this often-overlooked disease.
Fields of Study & Subjects
Ovarian function and disorders
Hormonal and reproductive studies
Hormonal Regulation and Hypertension
Publication details
- Journal / source
- Journal of Clinical Investigation
- Publisher
- American Society for Clinical Investigation
- Volume
- 136
- Issue
- 12
- Publication date
- 14 June 2026
- Language
- EN