New Horizons in the Development of Treatments for Substance Use Disorders

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Authors: John J. Mariani, Frances R. Levin
Cited by: 1
References: 123

Abstract

Substance use disorders (SUDs) are a major public health problem in the United States and cause substantial morbidity and mortality. There are meaningful gaps in the available SUD treatment options, and the development of new therapies is urgently needed. While medications with U.S. Food and Drug Administration approval are available for alcohol, nicotine, and opioid use disorders, there are no approved pharmacotherapies for cannabis, cocaine, or methamphetamine use disorders. Behavioral treatments for SUDs have significant limitations in effectiveness and accessibility, and there is a need for the development of both new behavioral treatment options and new models of treatment delivery. The next generation of treatments for SUDs will likely come from a diverse set of interventions, including new drug classes, new technologies, and new methods of delivery.

Fields of Study & Subjects

Substance Abuse Treatment and Outcomes Opioid Use Disorder Treatment Forensic Toxicology and Drug Analysis

Publication details

Journal / source
American Journal of Psychiatry
Publisher
American Psychiatric Association Publishing
Volume
183
Issue
9
Pages
615–623
Publication date
1 September 2026
Language
EN