Factors Affecting Maternal Respiratory Syncytial Virus Vaccination and the Impact on Infant Hospitalization During the 2023-2024 Season in Dallas, Texas

Objectives: This study assessed factors associated with respiratory syncytial virus (RSV) immunization rates among pregnant women and evaluated the effectiveness of maternal RSV vaccination on infant hospitalization rates. Methods: We collected data on mothers and their newborns born at a university-affiliated hospital in Dallas, Texas, during the 2023-2024 RSV season if they responded to a telephone survey and confirmed their vaccination status. We used logistic regression to assess associations between demographic factors and receipt of maternal RSV vaccination. We confirmed infant RSV hospitalization by telephone survey and calculated maternal RSV vaccination effectiveness against RSV-associated hospitalization. Results: From November 1, 2023, through February 29, 2024, 179 of 656 women (27%) received the maternal RSV vaccine. Women aged