Guillain–Barré syndrome with unilateral oculomotor nerve palsy and anti-GM3 IgG antibodies
Abstract
Guillain-Barré syndrome (GBS) is a life-threatening acute paralytic neuropathy characterized by rapidly progressive limb weakness and bilateral cranial nerve involvement. We report an early 70s male with no relevant medical history diagnosed with anti-GM3 IgG-positive GBS, who developed unilateral oculomotor nerve palsy and autonomic dysfunction during intravenous immunoglobulin (IVIG) therapy, with spontaneous symptom resolution following IVIG completion. Six-month follow-up assessments confirmed complete remission. This case reinforces the therapeutic value of IVIG in GBS patients with specific autoantibody profiles, even when complicated by transient neurological deterioration during treatment.
Fields of Study & Subjects
Peripheral Neuropathies and Disorders
Autoimmune Neurological Disorders and Treatments
Peripheral Nerve Disorders
Publication details
- Journal / source
- Science Progress
- Volume
- 109
- Issue
- 1
- Pages
- 368504251406582–368504251406582
- Publication date
- 1 January 2026
- Language
- EN