The clinical relevance of the COVID-19-associated hyperinflammatory syndrome score in the ICU: A single-center retrospective observational study

Science Progress 2026 Open access

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Authors: Jasmina Smajić, Fatima Iljazagić-Halilović, Lejla Mujkic, Selma Sijerčić, Ena Smajic, Samir Delibegović
DOI: 10.1177/00368504261421431
Cited by: 0
References: 13

Abstract

ObjectivesThe COVID-19-associated hyperinflammatory syndrome (cHIS) score has been proposed as a tool for identifying patients at risk of clinical deterioration. This study evaluated the predictive accuracy of the admission cHIS score for invasive mechanical ventilation and ICU mortality in critically ill COVID-19 patients.MethodsWe conducted a single-center retrospective observational study including 85 adults with laboratory-confirmed COVID-19 who were admitted to the ICU. The cHIS score was calculated on admission, and patients were stratified into two groups (

Fields of Study & Subjects

COVID-19 Clinical Research Studies Sepsis Diagnosis and Treatment Respiratory Support and Mechanisms

Publication details

Journal / source
Science Progress
Volume
109
Issue
1
Pages
368504261421431–368504261421431
Publication date
1 January 2026
Language
EN