Neurobiology and neuropharmacology of zebrafish social behavior

Journal of Psychopharmacology 2026

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Authors: Kirill V. Apukhtin, V. D. Riga, М. М. Kotova, David S. Galstyan, LongEn Yang, Jiahao Cui, Lee Wei Lim, Murilo S. de Abreu, Allan V. Kalueff
DOI: 10.1177/02698811251413496
Cited by: 2
References: 348

Abstract

) displays a wide range of robust and quantifiable social phenotypes, including shoaling/schooling, social preference and learning, as well as aggression and mating behaviors. Zebrafish social behavior is influenced by various neurotransmitters and hormones (including serotonin, dopamine, isotocin, cortisol, and endocannabinoids) and can be modulated experimentally, including genetically and pharmacologically. Here, we summarize current knowledge on neurobiology and neuropharmacology of zebrafish social behavior, and discuss various effects of drugs and other manipulations that target this critical behavioral domain.

Fields of Study & Subjects

Zebrafish Biomedical Research Applications Cephalopods and Marine Biology Neuroendocrine regulation and behavior

Publication details

Journal / source
Journal of Psychopharmacology
Publisher
SAGE Publications
Volume
40
Issue
7
Pages
1118–1148
Publication date
15 February 2026
Language
EN