Lactate dehydrogenase-to-albumin ratio for the severity of coronary artery disease in acute myocardial infarction: A retrospective study

ObjectiveThis study aimed to explore the association between lactate dehydrogenase-to-albumin ratio and the severity of coronary artery disease in patients with acute myocardial infarction.MethodsPatients with acute myocardial infarction were categorized into three groups based on the lactate dehydrogenase-to-albumin ratio tertiles. Demographic characteristics and Gensini scores were collected. Logistic regression and the receiver operating characteristic analyses were performed to evaluate the predictive ability of the lactate dehydrogenase-to-albumin ratio for a high Gensini score (>60). The area under the curve was calculated.ResultsA total of 489 individuals were retrospectively enrolled in this study. Multivariate logistic regression analysis demonstrated that the highest lactate dehydrogenase-to-albumin ratio was an independent risk factor for a high Gensini score (odds ratio, 3.45; 95% confidence interval: 1.37-8.71; p = 0.009). The receiver operating characteristic analysis showed that the lactate dehydrogenase-to-albumin ratio had good predictive ability for identifying a high Gensini score (area under the curve, 0.743; 95% confidence interval: 0.698-0.788).ConclusionsLactate dehydrogenase-to-albumin ratio may serve as a novel indicator for predicting the severity of coronary artery disease in patients with acute myocardial infarction.