Central compartment atopic disease: Advances in pathogenesis and stratified treatment
Abstract
Central compartment atopic disease is a recently delineated inflammatory endotype of chronic rhinosinusitis. It is characterized by involvement of the central intranasal compartment-the middle turbinate, superior turbinate, and posterior superior nasal septum-and is associated with a predominantly polypoid phenotype. This review synthesizes current evidence on local allergic pathophysiology, diagnostic frameworks, and stratified management of central compartment atopic disease to facilitate accurate diagnosis and individualized treatment.
Fields of Study & Subjects
Sinusitis and nasal conditions
Nasal Surgery and Airway Studies
Allergic Rhinitis and Sensitization
Publication details
- Journal / source
- Journal of International Medical Research
- Publisher
- SAGE Publications
- Volume
- 54
- Issue
- 1
- Pages
- 3000605251413400–3000605251413400
- Publication date
- 1 January 2026
- Language
- EN