Safety Assessment of Glucosamine Ingredients as Used in Cosmetics

International Journal of Toxicology 2026

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Authors: Priya Ferguson, Wilma Fowler Bergfeld, Donald V. Belsito, David E. Cohen, Curtis D. Klaassen, Daniel C. Liebler, Allan E. Rettie, David Ross, Lisa A. Peterson, Ronald C. Shank, Thomas J Slaga, Paul W. Snyder
+3 more Susan C. Tilton, Monice M. Fiume, Bart A. Heldreth
DOI: 10.1177/10915818261425571
Cited by: 0
References: 37

Abstract

The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of Acetyl Glucosamine, Glucosamine, Glucosamine HCl, and Glucosamine Sulfate. Two of the ingredients, Acetyl Glucosamine and Glucosamine Sulfate, are reported to function in cosmetics as skin-conditioning agents, Glucosamine HCl is reported to function as a pH adjustor, and the function of Glucosamine in cosmetics is not reported. The Panel reviewed the available data and concluded that these glucosamine ingredients are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating.

Fields of Study & Subjects

Contact Dermatitis and Allergies Dermatology and Skin Diseases Dye analysis and toxicity

Publication details

Journal / source
International Journal of Toxicology
Volume
45
Issue
1_suppl
Pages
27S–47S
Publication date
1 February 2026
Language
EN