Recurrent Diffuse Chorioamniotic Hemosiderosis of the Placenta in a Mother With Congenital Heart Disease
Abstract
A woman in her mid-20s with repaired congenital heart disease (CHD) delivered a 33-week neonate in 2024 following preterm labor and a 24-week neonate in 2025 for non-reassuring fetal heart tones. Placental examination in both cases revealed grossly abnormal, red-brown discolored membranes with a circumvallate insertion. Histologic evaluation demonstrated diffuse chorioamniotic hemosiderosis (DCH) in both cases. This report describes a novel case of recurrent DCH in a mother with CHD and proposes that Fontan physiology may contribute to impaired uteroplacental perfusion, increasing the risk for marginal hemorrhage.
Fields of Study & Subjects
Maternal and fetal healthcare
Cardiovascular Issues in Pregnancy
Gestational Trophoblastic Disease Studies
Publication details
- Journal / source
- Pediatric and Developmental Pathology
- Volume
- 29
- Issue
- 2
- Pages
- 158–161
- Publication date
- 5 January 2026
- Language
- EN