Exercise for treatment and prevention of post-pulmonary embolism syndrome: A review

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Authors: Mateo Porres-Aguilar, Emma Johns, Gregory Piazza, Robert McBane, Ana I. Casanegra, Thomas Olson, Damon E. Houghton, Michael N Young, Stanislav Henkin
Cited by: 2
References: 53

Abstract

Post-pulmonary embolism syndrome (PPES) encompasses a diverse spectrum of long-term complications that are associated with persistent dyspnea, exercise intolerance, and a decrease in quality of life. The PPES constellation ranges from life-threatening conditions such as chronic thromboembolic pulmonary hypertension (CTEPH) to nonlife-threatening but still debilitating conditions such as chronic thromboembolic pulmonary disease (CTED) or post-PE deconditioning. The safety and efficacy of exercise and cardiopulmonary rehabilitation programs to prevent and manage these symptoms in PPES has not been well established. Herein, we review contributors to PPES and synthesize the evidence for exercise training after PE to treat and prevent PPES.

Fields of Study & Subjects

Venous Thromboembolism Diagnosis and Management Cardiovascular and exercise physiology Pulmonary Hypertension Research and Treatments

Publication details

Journal / source
Vascular Medicine
Publisher
SAGE Publications
Volume
31
Issue
3
Pages
409–420
Publication date
17 March 2026
Language
EN