Potential Role of Inhaled Insulin in the Management of Gestational Diabetes Mellitus and Pediatric Type 1 Diabetes

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Authors: Lori M. Laffel, Amy Miyoshi Valent
Cited by: 1
References: 96

Abstract

The management of diabetes in women with gestational diabetes and in children and adolescents with type 1 diabetes presents challenges that require therapeutic options that address the unique needs of these patients. Technosphere® insulin (TI), the main component of the Afrezza® Inhalation System, has the potential to address these challenges by improving glycemic management, reducing hypoglycemia, and promoting treatment adherence. TI is characterized by a rapid onset of action and a short duration of effect, distinguishing it from traditional injectable rapid-acting insulin analogs. This article discusses greater flexibility in insulin delivery, along with potential applications, benefits, and challenges of treatment with Technosphere inhaled insulin in these two patient populations.

Fields of Study & Subjects

Inhalation and Respiratory Drug Delivery Neonatal Respiratory Health Research Advanced Drug Delivery Systems

Publication details

Journal / source
Diabetes Technology & Therapeutics
Publisher
SAGE Publications
Volume
28
Issue
1_suppl
Pages
43S–54S
Publication date
1 February 2026
Language
EN