A case of retroperitoneal giant leiomyoma and literature review

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Authors: Zhuocheng Lai, Xiaojun Shi, Qiong Wang, Samir Lalani, Yiwei Wang, Yang Lian, Zaosong Zheng, Weiyu Huang, Shiyu Pang, Wanlong Tan
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References: 25

Abstract

Retroperitoneal fibroids are a rare condition that is often misdiagnosed preoperatively. It typically occurs in women with a history of hysterectomy or myomectomy for benign uterine smooth muscle tumors. In this case report, we present the case of a 50-year-old woman who presented with discomfort in the right perineal area. Imaging showed a large retroperitoneal tumor. The patient underwent robotic-assisted laparoscopic surgery to remove the mass, which was confirmed by histopathological analysis to be a uterine smooth muscle tumor of undetermined malignant potential (STUMP). The patient had no recurrence during the 2-year follow-up. The overall prognosis of STUMP is favorable, but more rigorous and long-term follow-up is required to monitor potential recurrence. Our case highlights that retroperitoneal masses in women with prior uterine fibroid surgery should raise suspicion for retroperitoneal fibroids. Robot-assisted laparoscopic surgery may be a safe and feasible minimally invasive option.

Fields of Study & Subjects

Uterine Myomas and Treatments Urologic and reproductive health conditions Soft tissue tumor case studies

Publication details

Journal / source
Therapeutic Advances in Urology
Volume
18
Pages
17562872251414923–17562872251414923
Publication date
1 January 2026
Language
EN