Design of Dry Powder Inhalers: 1. Does Size Matter?
Abstract
Regional deposition of inhaled medicines in the respiratory tract is heavily influenced by inertial impaction. Despite this, the current convention is to convert impaction parameter cutoffs on stages in impactors to size cutoffs by operating the impactor at a fixed flow rate. While such a practice has utility when using impactors as a quality control tool, a focus on size metrics (e.g., mass median aerodynamic diameter [MMAD] and fine particle fraction [FPF
Fields of Study & Subjects
Inhalation and Respiratory Drug Delivery
Asthma and respiratory diseases
Advancements in Transdermal Drug Delivery
Publication details
- Journal / source
- Journal of Aerosol Medicine and Pulmonary Drug Delivery
- Publisher
- SAGE Publications
- Volume
- 39
- Issue
- 3
- Pages
- 141–154
- Publication date
- 15 January 2026
- Language
- EN