Esophageal nerve sheath tumor: A rare benign tumor with diagnostic challenges—A case report
Abstract
Esophageal nerve sheath tumors are the least common type of esophageal submucosal tumors, with fewer than 60 cases reported in the literature. 1 These tumors typically occur as a solitary lesion in individuals aged 40–70, with a slight female predominance 2 and possible links to genetic syndromes such as neurofibromatosis type 2. 3 Due to their rarity, they are often poorly recognized clinically and misdiagnosed prior to surgery. We present a rare case of esophageal nerve sheath tumor, diagnosed on esophagogastroduodenoscopy in a 46-year-old male who presented with chronic iron deficiency anemia. The patient was successfully treated with endoscopic submucosal dissection. This case highlights diagnostic and therapeutic considerations of this uncommon entity.
Fields of Study & Subjects
Gastrointestinal Tumor Research and Treatment
Neurofibromatosis and Schwannoma Cases
Esophageal Cancer Research and Treatment
Publication details
- Journal / source
- SAGE Open Medical Case Reports
- Publisher
- SAGE Publications
- Volume
- 14
- Pages
- 2050313X251411147–2050313X251411147
- Publication date
- 1 January 2026
- Language
- EN