Delivering HPV results via telehealth: Patient needs and engagement following an at-home self-collection study

Objective This study evaluated the complete patient experience of at-home self-collection for cervical cancer screening using the Teal Wand, the United States Food and Drug Administration (FDA)-authorized vaginal self-collection device, paired with a Health Insurance Portability and Accountability Act (HIPAA)-secure telehealth platform. Introduction The data assesses patients’ understanding, experiences, and engagement, particularly around results delivery. The findings inform telehealth strategies that can improve patients’ human papillomavirus (HPV) results experience, build HPV awareness, facilitate follow-up care when needed, and increase screening adherence. Methods A prospective, mixed-methods cohort usability study was conducted using structured surveys and in-depth interviews, supplemental to prospective clinical validation. Thirty participants used the Teal Wand and completed surveys after major touchpoints. A subset ( n = 10) participated in semi-structured interviews. Surveys captured usability, satisfaction, comprehension, and overall experience. Interviews were analyzed using an abductive approach. Platform analytics provide further insight into utilization. Results All participants (30/30) completed self-collection, with 4.7/5 average satisfaction score. Most (93%) found the platform easily navigable and results easy to access and understand. All participants viewed results within 1.5 hours on average and understood next steps. Among those needing follow-up ( n = 9), 100% scheduled follow-up telehealth appointments within hours of viewing results, and all attended those appointments. Qualitative data underscored the importance of supportive language and provider engagement in mitigating emotional distress, especially for HPV-positive results. Conclusions At-home cervical cancer screening supported by a tailored telehealth platform is usable and acceptable. Thoughtful results delivery can improve patient comprehension, reduce anxiety, and strengthen future adherence, supporting broader efforts to increase screening access and reduce cervical cancer burden.