Elective Lumbar Decompression With Fusion Is Associated With Increased Mortality Compared With Decompression Alone: A National Propensity-Matched Analysis of Aging Cohorts

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Authors: Alec M Giakas, William A. Green, Mitchell K. Ng, Molly E. Milano, Yulia Lee, Anthony Castro, Jonathan Dalton, Brandon Martinazzi, Ali S. Farooqi, Daniel Gallagher, Eric Tecce, Alexandra Dionne
+6 more Andrew Alvarez, Daniel Fassett, Alan S. Hilibrand, Alexander R. Vaccaro, Christopher Kepler, Gregory Schroeder
Cited by: 1
References: 48

Abstract

Study DesignPropensity-matched cohort study.ObjectivesTo evaluate short/mid-term safety and mortality of elective lumbar decompression alone (LD) versus lumbar decompression with fusion (LDF) for degenerative lumbar disease in octogenarians and the aging patient.MethodsThe TriNetX research network was queried for adults with degenerative lumbar disease who underwent LD or LDF (2012-2025). Patients with deformity, instability, spondylolisthesis, or congenital malformation were excluded. Patients were stratified by decade of life (60-69, 70-79, 80-89 years) and matched 1:1 for demographics, steroid use, lipoprotein disorders, and modified Frailty Index-5 comorbidities. Outcomes were compared at 30 days, 90 days, 1 year, and 2 years. The primary outcome was mortality; secondary outcomes included medical and surgical complications.ResultsAcross all age decades, LDF was associated with >5-fold higher 30-day mortality (OR 5.16-6.34, all p3.5-fold higher 90-day mortality (OR 3.83-6.35, all p

Fields of Study & Subjects

Spine and Intervertebral Disc Pathology Cervical and Thoracic Myelopathy Scoliosis diagnosis and treatment

Publication details

Journal / source
Global Spine Journal
Publisher
SAGE Publications
Pages
21925682261474435–21925682261474435
Publication date
30 July 2026
Language
EN