Substance use may be associated with non-adherence to non-invasive ventilation in adults with myotonic dystrophy type 1
Abstract
Adults with myotonic dystrophy type 1 who require non-invasive ventilation (NIV) often have difficulty with adherence. Few risk factors for non-adherence have been identified, and these are mostly unmodifiable. As part of a quality assurance initiative, we sought to identify psychosocial barriers to NIV adherence to improve supports around isolation and mental health. We found that substance use was associated with non-adherence to NIV in our cohort. Cognitive impairment, the receipt of provincial income support, presence of a psychiatric condition, living alone, and marital status were not associated with NIV adherence. Interventions that limit the impact of substance use may improve NIV in this population.
Fields of Study & Subjects
Respiratory Support and Mechanisms
Obstructive Sleep Apnea Research
Medication Adherence and Compliance
Publication details
- Journal / source
- Journal of Neuromuscular Diseases
- Volume
- 13
- Issue
- 5
- Pages
- 1176–1178
- Publication date
- 4 February 2026
- Language
- EN