Neural and Behavioral Effects of Harp Music: Frontal Alpha Suppression and Reaction Times in Relation to Depression-Related Traits

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Authors: Misako Matsui, Yuri Masaoka, Nobuyoshi Koiwa, Motoyasu Honma, Akira Yoshikawa, Shota Kosuge, Miku Kosuge, Daiki Shoji, Shunsuke Sakakura, Katsunori Inagaki, Masahiko Izumizaki
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References: 25

Abstract

Background/ObjectivesHarp music has long been used for comfort and healing, yet its neural mechanisms remain unclear. This study examined how major and minor harp sounds influence frontal alpha activity, mood, and reaction times, with a focus on depression-related individual differences.MethodsParticipants listened to 3-min major and minor harp excerpts while EEG alpha activity was recorded. Subjective ratings of arousal, stress, comfort, and mood were assessed, followed by auditory and visual reaction-time tasks.ResultsIndividuals with lower depression scores showed marked frontal alpha suppression during harp listening, which was associated with faster auditory reaction times. Those with higher depression scores exhibited consistently lower frontal alpha power with minimal modulation by harp sounds.ConclusionsFrontal alpha suppression during harp listening may reflect enhanced auditory attentional processing in individuals with lower depression levels. These findings suggest that depression-related traits shape neural responsiveness to harp music and should be considered when evaluating its therapeutic potential.

Fields of Study & Subjects

Music Therapy and Health Neuroscience and Music Perception Neural dynamics and brain function

Publication details

Journal / source
Journal of Evidence-Based Integrative Medicine
Volume
31
Pages
2515690X261418393–2515690X261418393
Publication date
1 January 2026
Language
EN