[Comparison of the efficacy of trabeculectomy combined with Schlemm canal incision versus trabeculectomy alone in the treatment of primary open angle glaucoma].

OBJECTIVES: Glaucoma is the leading cause of irreversible blindness worldwide, with primary open-angle glaucoma (POAG) being the most common type. Trabeculectomy is currently the primary surgical treatment for POAG; however, its long-term efficacy remains suboptimal. This study aims to compare the therapeutic efficacy and safety of trabeculectomy combined with Schlemm canal incision (TCSCI) with trabeculectomy alone in order to provide new insights for POAG management. METHODS: In this retrospective case-control study, 47 patients (47 eyes) diagnosed with POAG at the Ophthalmology Center of Xiangya Hospital between May 2019 and May 2023 were included. Patients undergoing combined trabeculectomy and Schlemm canal incision were assigned to the TCSCI group, whereas those undergoing trabeculectomy alone were assigned to the trabeculectomy group. Postoperative assessments or follow-up were conducted on postoperative day 1 and at 1 week, 1 month, 2 months, 3 months, 6 months, 1 year, and 2 years. Best-corrected visual acuity, intraocular pressure (IOP), number of glaucoma medications, surgical success rate, and intraoperative and postoperative complications were compared between groups. RESULTS: