The telomeric puzzle in TP53 -mutant myeloid neoplasms

Blood 2026 Open access

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Authors: Ing Soo Tiong, Lucy C. Fox
DOI: 10.1182/blood.2025031124
Cited by: 0
References: 9

Abstract

In this issue of Blood, Guarnera et al 1 report that telomere content (TC) in specific myeloid neoplasm subgroups (particularly those with complex karyotype and biallelic TP53 mutations) is unexpectedly similar to that in nonmalignant controls, whereas overall myeloid neoplasms generally have lower TC.

Fields of Study & Subjects

Acute Myeloid Leukemia Research Telomeres Telomerase and Senescence Cancer-related Molecular Pathways

Publication details

Journal / source
Blood
Volume
147
Issue
2
Pages
102–103
Publication date
8 January 2026
Language
EN