Sirolimus for refractory/relapsed warm autoimmune hemolytic anemia and Evans syndrome: a prospective study

Blood Advances 2026 Open access

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Authors: qi wang, Ziwei Liu, Chen Yang, Jian Li, M Chen, B F Han
DOI: 10.1182/bloodadvances.2026019844
Cited by: 1
References: 29

Abstract

ABSTRACT: Effective therapeutic options remain limited for adults with relapsed or refractory (R/R) warm autoimmune hemolytic anemia (wAIHA) and Evans syndrome (ES). We conducted a prospective, single-center, open-label clinical trial to evaluate the efficacy and safety of sirolimus. Adult patients with R/R wAIHA or ES and hemoglobin levels

Fields of Study & Subjects

Blood groups and transfusion Erythrocyte Function and Pathophysiology Blood transfusion and management

Publication details

Journal / source
Blood Advances
Publisher
American Society of Hematology
Volume
10
Issue
18
Pages
6198–6207
Publication date
9 June 2026
Language
EN