Outcomes of patients receiving acute non-invasive ventilation (NIV) at a tertiary hospital

Introduction: Acute NIV is widely used in managing acute hypercapnic respiratory failure in chronic respiratory conditions. Despite established guidelines, real-world outcomes vary due to multiple factors such as patient selection, timing of initiation and escalation decisions. Understanding local outcomes and predictors of success can inform service improvement. Aims & Objectives: The aim of this project is to examine the patient cohort who required NIV during a 2-month period at Norfolk and Norwich University Hospital. We then explored the impact of receiving NIV – examining the healthcare utilisation post discharge and mortality. Methods: We analysed the characteristics of patients who required NIV over a 2-month period. This included the underlying chronic respiratory comorbidity. We followed these patients for a further 5 months to see if there were any readmissions post NIV or mortality. Results: Among 34 patients (median age 60–69 years, 52.9% female), COPD was the leading indication for NIV (55.9%). Readmission rate was highest in COPD compared to OHS, whereas survival was better in OHS compared to COPD. Conclusion: Our real-world data shows clinically meaningful outcomes after initiating Acute NIV. erjor;12/suppl_17/115/F1 F1 F1