Andersen-Tawil syndrome with high-burden ventricular arrhythmias: a case report

BMC Cardiovascular Disorders 2026 Open access

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Authors: Ruiting Feng, Jia Gao, Yuli Guo, Zengfu Zhang, Xiaohong Fu, Rui Wang, Min Guo
DOI: 10.1186/s12872-026-05649-4
Cited by: 1
References: 8

Abstract

Andersen-Tawil syndrome (ATS) is a rare autosomal dominant genetic disorder. Its main clinical manifestations include severe ventricular arrhythmias (VA), periodic paralysis, and facial and skeletal dysplasia. Due to the lack of awareness of this disease, it is highly prone to missed diagnosis and misdiagnosis. This case report presents a young female who presented with abnormal electrocardiogram during physical examination, had poor efficacy after radiofrequency ablation treatment, and was finally diagnosed with Andersen-Tawil syndrome (ATS) by genetic testing, providing a reference for the diagnosis and treatment of this rare clinical disease.

Fields of Study & Subjects

Glycogen Storage Diseases and Myoclonus Ion Transport and Channel Regulation Ion channel regulation and function

Publication details

Journal / source
BMC Cardiovascular Disorders
Publisher
Springer Science and Business Media LLC
Volume
26
Issue
1
Publication date
25 February 2026
Language
EN