Maternal and fetal outcomes in patients with congenital heart disease associated with pulmonary arterial hypertension in high-altitude areas: a retrospective cohort study

BMC Pregnancy and Childbirth 2026 Open access

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Authors: Xiang-Ting Lu, Xuerong Chen, Qing Jin, Yun-Yan Xu, Pei-Yun Jin, Yi-Bing Lu, Hai-Long Dai
DOI: 10.1186/s12884-026-09340-6
Cited by: 1
References: 35

Abstract

OBJECTIVES: Pulmonary arterial hypertension associated with congenital heart disease (CHD-PAH) increases maternal and fetal risk. This study aimed to analyze maternal and fetal outcomes in patients with CHD-PAH in high-altitude areas. METHODS: The pregnant women with CHD were analyzed retrospectively from 2012 to 2022. Pulmonary artery systolic pressure (PASP) was estimated by echocardiography. Patients were categorized into four groups: no PAH (PASP < 40 mmHg), mild (40 mmHg≤PASP < 50 mmHg), moderate (50 mmHg≤PASP < 70 mmHg) and severe PAH (PASP ≥ 70 mmHg). RESULTS:

Fields of Study & Subjects

Pulmonary Hypertension Research and Treatments Cardiovascular Issues in Pregnancy Congenital Heart Disease Studies

Publication details

Journal / source
BMC Pregnancy and Childbirth
Publisher
Springer Science and Business Media LLC
Volume
26
Issue
1
Publication date
28 May 2026
Language
EN