Serum albumin-creatinine ratio predicts sarcopenia and poor outcomes in patients with colorectal cancer

Abstract Background: This study was designed to explore the prognostic significance of the serum albumin-creatinine ratio (ACR) in patients with colorectal cancer (CRC). Methods: Kaplan-Meier survival analysis was utilized to evaluate overall survival (OS) and progression-free survival (PFS). Cox proportional hazards regression models were applied to identify independent prognostic factors. A nomogram based on the ACR was developed to predict 1-, 3-, and 5-year survival probabilities. Results: A total of 1438 patients were included in this study. Patients with a high ACR (≥38.5) had significantly worse outcomes compared with those having a low ACR (