Kinematic alignment yields a reduced knee adduction moment and better range of motion compared to mechanical alignment: biomechanical considerations of a staged, bilateral total knee arthroplasty case

BMC Musculoskeletal Disorders 2026 Open access

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Authors: Letizia Mancini, Giovanni Spallone, Arianna Carnevale, Stefano Campi, Carlo Casciaro, Emiliano Schena, Pieter P. R. N. d’Hooghe, REHA NEVZAT TANDOGAN, Rocco Papalia, UG Longo
DOI: 10.1186/s12891-025-09445-7
Cited by: 1
References: 48

Abstract

This technical note describes an intra-subject comparison between mechanical and kinematic alignment in total knee arthroplasty (TKA), based on gait analysis performed before and after staged bilateral procedures. Our quantitative assessment revealed differences in joint range of motion, moment profiles, and ground reaction forces between the two limbs. The kinematically aligned knee showed greater multi-planar mobility, higher sagittal moments, and a more physiological gait pattern. These findings highlight the added value of dynamic biomechanical analysis in evaluating the functional impact of alignment strategies, offering insights that go beyond static imaging and supporting more personalized approaches in TKA.

Fields of Study & Subjects

Total Knee Arthroplasty Outcomes Knee injuries and reconstruction techniques Orthopaedic implants and arthroplasty

Publication details

Journal / source
BMC Musculoskeletal Disorders
Publisher
Springer Science and Business Media LLC
Volume
27
Issue
1
Pages
108–108
Publication date
30 January 2026
Language
EN