Surgical outcomes of endoscopic endonasal surgery for nonfunctioning pituitary adenoma in elderly patients: a comprehensive analysis beyond age

BMC Endocrine Disorders 2026 Open access

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Authors: Sun Mo Nam, Jong Ha Hwang, Hye Seok Park, Seung Shin Park, J. Kim, Min-Sung Kim, Chul-Kee Park, Hee-Pyoung Park, Yong Hwy Kim
DOI: 10.1186/s12902-026-02173-6
Cited by: 0
References: 44

Abstract

BACKGROUND: Due to the rapid aging of the global population, it is challenging to identify elderly individuals who are optimal candidates for the surgical treatment of pituitary neuroendocrine tumors. While chronological age has traditionally influenced surgical decision-making, the independent effect of age on outcomes requires a comprehensive evaluation that controls for comorbidities and tumor characteristics. METHODS: This retrospective analysis included 305 patients (≥18 years) who underwent endoscopic endonasal surgery for clinically nonfunctioning pituitary neuroendocrine tumors between March 2020 and February 2024 at a single tertiary center. Patients were stratified by age (

Fields of Study & Subjects

Pituitary Gland Disorders and Treatments Head and Neck Surgical Oncology Neuroendocrine Tumor Research Advances

Publication details

Journal / source
BMC Endocrine Disorders
Volume
26
Issue
1
Pages
69–69
Publication date
12 February 2026
Language
EN