COPD in China: the analysis of mortality and burden of disease trends from 2008 to 2021

To determine basic death situation and assess trends in disease burden, we analyzed the death information of Chronic Obstructive Pulmonary Disease (COPD) among Chinese residents from 2008 to 2021. Data were collected from the Cause-of-Death Surveillance dataset in China. The Crude Mortality Rate (CMR), Age-Standardized Mortality Rate (ASMR), Potential Years of Life Lost (PYLL), and Potential Years of Life Lost Rate (PYLLR) of COPD among Chinese residents from 2008 to 2021 were calculated by Excel 2016. The trends of ASMR and PYLLR were assessed by the average annual percentage change (AAPC), and the difference in mortality was tested by Chi-square tests(χ 2 tests). The age, period, and cohort effects on COPD mortality were analyzed by the Age-Period-Cohort (APC) model. The ASMR of COPD in Chinese residents decreased from 78.84/100,000 in 2008 to 27.81/100,000 in 2021 at an average annual rate of 8.41%, and the PYLLR of COPD in Chinese residents decreased from 1.28‰ in 2008 to 0.53‰ in 2021 at an average annual rate of 6.06%. From 2008 to 2021, the COPD ASMR and PYLLR among Chinese males were higher than females, urban areas were lower than rural areas, western China was higher than central China, and central China was higher than that in eastern China. The decline rate of COPD ASMR and PYLLR was significantly higher in females than males, rural areas than urban areas, and eastern/central regions than western regions. The mortality and disease burdens of COPD in China decreased yearly and were higher in the elderly, males, rural areas, and western China. The disease burden of COPD decreased more rapidly in women, rural areas, eastern and central China.