Is congenital thrombotic thrombocytopenic purpura a risk factor for ischemic osteonecrosis of the hip joint (Legg-Calvé-Perthes disease)?

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Authors: Alexander Laemmle, Bernhard Lämmle
Cited by: 0
References: 19

Abstract

Weise et al. reported on a 41-year-old patient previously diagnosed with congenital thrombotic thrombocytopenic purpura undergoing total hip replacement surgery for Perthes disease. This case raises the question whether ischemic osteonecrosis of the femoral head is another so far underrecognized comorbidity causally linked to congenital thrombotic thrombocytopenic purpura.

Fields of Study & Subjects

Complement system in diseases Bone and Joint Diseases Blood Coagulation and Thrombosis Mechanisms

Publication details

Journal / source
Thrombosis Journal
Volume
24
Issue
1
Pages
23–23
Publication date
12 February 2026
Language
EN