Infectious retinitis associated with JAK inhibitors: the ongoing duality of JAK inhibitors
Abstract
PURPOSE: To discuss the recent evidence that Janus kinase (JAK) inhibitors can cause viral retinitis. METHODS: A commentary on the case report in this issue and a review of cases in the literature. RESULTS: A total of 6 cases have now been reported of cytomegalovirus retinitis associated with Jak inhibitors. Additionally, there was a case of bilateral toxoplasma retinitis and a case of herpetic scleritis. DISCUSSION: It is important to be aware of the potential blinding complications associated with JAK inhibitors and if the patient complains of acute vision loss and/or floaters, the patient should be emergently referred to a retina specialist.
Fields of Study & Subjects
Drug-Induced Ocular Toxicity
Ocular Diseases and Behçet’s Syndrome
Ocular Infections and Treatments
Publication details
- Journal / source
- International Journal of Retina and Vitreous
- Volume
- 12
- Issue
- 1
- Publication date
- 6 March 2026
- Language
- EN