Polysomnographic characteristics of migraine patients: a comparative clinical study

Abstract Introduction Sleep disturbances are common in patients with migraine, and studies related to sleep architecture changes in those patients are few in the literature. In this study, the aim is to investigate sleep quality in patients with migraine, identifying polysomnographic abnormalities compared to healthy controls, and to correlate the different polysomnographic parameters and severity of headaches. Methods This study was conducted on forty patients with migraine and forty healthy volunteers, as controls, of matching age and sex. The severity of headaches was assessed using the migraine disability assessment score (MIDAS). Sleep was assessed by the Pittsburgh Sleep Quality Index (PSQI) and overnight polysomnography (PSG) . Results In patients with migraine, the sleep architecture was worse, including low sleep efficiency( p < 0.001), prolonged sleep latency, reduced stage N3 sleep( p < 0.001), increased arousal index, and more frequent sleep stage change compared to healthy controls. Furthermore, There was a statistically significant correlation between migraine severity (MIDAS) in the patient group and sleep quality (PSQI) ( p < 0.001).