Female-specific Cx3cr1-driven regulation of ALS and Alzheimer’s risk genes in tauopathy

Molecular Neurodegeneration Advances 2026 Open access

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Authors: Ari Sudwarts, Gopal Thinakaran
DOI: 10.1186/s44477-026-00022-3
Cited by: 0
References: 10

Abstract

in the P301S (PS19) transgenic model of tau pathology, we report remarkable transcriptional changes, including crucial amyotrophic lateral sclerosis and Alzheimer's disease risk genes, several of which showed co-expression, suggesting gene-gene interactions among these genetic risk factors. Supplementary Information: The online version contains supplementary material available at 10.1186/s44477-026-00022-3.

Fields of Study & Subjects

Alzheimer's disease research and treatments Neuroinflammation and Neurodegeneration Mechanisms Amyotrophic Lateral Sclerosis Research

Publication details

Journal / source
Molecular Neurodegeneration Advances
Volume
2
Issue
1
Pages
16–16
Publication date
8 March 2026
Language
EN