Silent struggles: sexual side-effects of selective serotonin reuptake inhibitors in adolescents

SUMMARY Selective serotonin reuptake inhibitors (SSRIs) are a key treatment for adolescent depression and anxiety, yet their sexual side-effects are often overlooked. Although well-documented in adults, sexual side-effects in adolescents remain under-researched and rarely discussed in clinical practice. This lack of awareness can contribute to distress, self-esteem issues and treatment non-adherence. Adolescence is a crucial time for sexual development, making recognition of sexual side-effects particularly important. However, young patients may not report these effects because of embarrassment or unawareness, and clinicians may avoid the topic because of discomfort or time constraints. By addressing sexual side-effects proactively, as highlighted in this article, clinicians can improve patient engagement, treatment or management adherence and overall mental well-being.