Combination Chemotherapy, Bevacizumab, Atezolizumab Prolongs PFS Over Atezolizumab Alone in dMMR/MSI-H mCRC

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Abstract

The combination of FOLFOX chemotherapy, bevacizumab, and atezolizumab yields significantly improved progression-free survival and response rates over atezolizumab monotherapy in patients with previously untreated deficient DNA mismatch repair or microsatellite instability–high metastatic colorectal cancer, according to new results from the phase 3 COMMIT study (Abstract 14).

Fields of Study & Subjects

Colorectal Cancer Treatments and Studies Genetic factors in colorectal cancer Cancer Immunotherapy and Biomarkers

Publication details

Journal / source
Default Digital Object Group
Publication date
10 January 2026
Document type
Dataset