Combination Enzalutamide and Radium-223 Extends OS in Bone-Dominant mCRPC in Phase 3 Trial

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Abstract

The addition of radium-223 to enzalutamide significantly improves OS in patients with bone-dominant mCRPC over enzalutamide alone, with an acceptable toxicity profile, according to results from the EORTC-1333/PEACE-3 trial (Abstract 15). Median OS was 38.2 months with enzalutamide plus radium-223 compared with 32.6 months with enzalutamide alone.

Fields of Study & Subjects

Prostate Cancer Treatment and Research Bone health and treatments Prostate Cancer Diagnosis and Treatment

Publication details

Journal / source
Default Digital Object Group
Publication date
26 February 2026
Language
EN
Document type
Dataset