Genetic variation and regulation of MICA alters natural killer cell-mediated immunosurveillance in early-onset colorectal cancer.

Journal of Clinical Oncology 2026

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Authors: Heather M. McGee, Joseph D. Bonner, Colt A. Egelston, Yubo Fu, Ferrán Moratalla-Navarro, Oscar Colunga Flores, Sidney A. Smith, Lawrence Shaktah, Yasmin Kamal, Kevin K. Tsang, Gregory Idos, Kevin J. McDonnell
+7 more Christopher Walker, Terence Marques Williams, Stanley R. Hamilton, James W. Gauderman, Victor Rau Moreno, Gad Rennert, Stephen B. Gruber
DOI: 10.1200/jco.2026.44.2_suppl.207
Cited by: 0

Abstract

207 Background: One of the most concerning trends in oncology is the rapid increase in the incidence of early-onset cancers, such as colorectal cancer, in patients

Fields of Study & Subjects

Immune Cell Function and Interaction Genetic factors in colorectal cancer Cancer Immunotherapy and Biomarkers

Publication details

Journal / source
Journal of Clinical Oncology
Volume
44
Issue
2_suppl
Pages
207–207
Publication date
10 January 2026
Language
EN