Real-world molecular profile and treatment patterns in advanced gastroesophageal adenocarcinoma: A Brazilian multicenter cohort.

Journal of Clinical Oncology 2026 Open access

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Authors: Mateus Zapparoli Claro, Renata D’Alpino Peixoto, Mauro Daniel Spina Donadio, Amanda Muniz Rodrigues, Rafael Duarte Paes, Alexandre Andrade dos Anjos Jacome, Rodrigo Dienstmann
DOI: 10.1200/jco.2026.44.2_suppl.313
Cited by: 0

Abstract

313 Background: Advanced (A) gastroesophageal adenocarcinoma (GA) prognosis remains poor, with limited data on molecular profiles and treatment in resource-diverse populations. Methods: We retrospectively analyzed clinical and molecular data from GA patients who underwent biomarker testing in centralized laboratories between January 2021 and June 2024. Patients were categorized by PD-L1 combined positive score (CPS:

Fields of Study & Subjects

Gastric Cancer Management and Outcomes Cancer Immunotherapy and Biomarkers Esophageal Cancer Research and Treatment

Publication details

Journal / source
Journal of Clinical Oncology
Volume
44
Issue
2_suppl
Pages
313–313
Publication date
10 January 2026
Language
EN