Comparative outcomes of pancreatic versus duodenal adenocarcinoma: A National Cancer Database analysis.
Abstract
686 Background: Pancreatic and duodenal adenocarcinomas share anatomic proximity but may differ in tumor biology, treatment patterns, and outcomes. Limited large-scale comparative data exist. We utilized the National Cancer Database (NCDB) to examine clinicopathologic features and survival outcomes between these two malignancies. Methods: We identified patients diagnosed with pancreatic (n=53,177) or duodenal (n=4,765) adenocarcinoma in the NCDB. Demographic, clinical, and treatment variables were compared using chi-square and Wilcoxon rank-sum tests. Survival was assessed with Kaplan–Meier analysis and log-rank testing, stratified by stage and surgical resection. Results: Duodenal cancer patients were slightly older (median 70 vs. 68 years, p
Fields of Study & Subjects
Pancreatic and Hepatic Oncology Research
Gastric Cancer Management and Outcomes
Cholangiocarcinoma and Gallbladder Cancer Studies
Publication details
- Journal / source
- Journal of Clinical Oncology
- Volume
- 44
- Issue
- 2_suppl
- Pages
- 686–686
- Publication date
- 10 January 2026
- Language
- EN