Optimizing nutrition in patients with pancreatic cancer (NUANCE study).

Journal of Clinical Oncology 2026

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Authors: Ronan Andrew McLaughlin, Shari L. Moura, Sarah Buchanan, Lorena Lazar, Daniela Bevacqua, Shiyi Chen, Stephanie Ramotar, Edith Bardi, Shawn Hutchinson, Rachel Ding, Martine T.E. Puts, Syeda Mariam Hasnain
+7 more Robert C. Grant, Raymond Woo-Jun Jang, Erica S. Tsang, Xin Wang, Elena C. Elimova, Anna Dodd, Jennifer Jane Knox
DOI: 10.1200/jco.2026.44.2_suppl.696
Cited by: 0

Abstract

696 Background: Patients (pts) with advanced pancreatic ductal adenocarcinoma (PDAC) experience significantly worse outcomes when nutritional support is inadequate; characterized by weight loss, GI symptoms, and metabolic derangements. These correlate with increased toxicity, reduced survival, and diminished quality of life. Prior prospective cohorts 1 highlight that most pts deteriorate nutritionally from baseline with a significant reduction in weight (p

Fields of Study & Subjects

Pancreatic and Hepatic Oncology Research Nutrition and Health in Aging Clinical Nutrition and Gastroenterology

Publication details

Journal / source
Journal of Clinical Oncology
Volume
44
Issue
2_suppl
Pages
696–696
Publication date
10 January 2026
Language
EN