Procedure-specific mortality risk in octogenarians undergoing curative GI cancer resection: A contemporary U.S. analysis.

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Authors: Canan Dilay Dirican, Ahmad Mardini, Hamza Ansari, Bugra Zengin, Michael Maroules
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Abstract

737 Background: Octogenarians increasingly undergo curative GI cancer surgery, yet most risk tools apply a uniform “age penalty” across procedures. Whether age ≥80 confers similar operative mortality across resections is unclear. We examined if the mortality impact of advanced age differs between pancreatic resection and gastrectomy. Methods: We used a nationally representative U.S. inpatient dataset (2020–2022) to identify adults with pancreatic or gastric cancer who underwent the corresponding resection. The primary outcome was in-hospital mortality; secondary outcomes were length of stay (LOS), and hospital charges. Multivariable models adjusted for sex, hospital teaching status, and year. An age (≥80 vs

Fields of Study & Subjects

Frailty in Older Adults Pancreatic and Hepatic Oncology Research Cardiac Anesthesia and Surgical Outcomes

Publication details

Journal / source
Journal of Clinical Oncology
Volume
44
Issue
2_suppl
Pages
737–737
Publication date
10 January 2026
Language
EN