Long-term survival trends in GI cancer: Demographic and socioeconomic influences.

810 Background: Gastrointestinal (GI) cancers including esophageal, gastric, colorectal, hepatobiliary, and pancreatic malignancies are among the leading causes of cancer-related morbidity and mortality worldwide. According to the 2020 GLOBOCAN report, one in every sixteen persons globally will die from GI cancer at some point in their lives. Even with the advancements in diagnostics and treatments, there are still substantial disparities in survival outcomes based on cancer subtype, age, sex, and socioeconomic status. Only a small number of studies have thoroughly investigated survival trends in the U.S. population stratified by age, sex, income, and follow-up time. Methods: Survival data were extracted from the SEER (Surveillance, Epidemiology, and End Results) database for patients diagnosed with GI cancers between 2000 and 2023. Analyses were stratified by age (