Primordial Germ Cells Migrate to the Gonad

CRC Press eBooks 2026 Book chapter

View at publisher
Authors: Gary M. Wessel, Julian L. Wong, Carmen J. Williams, Mark A. Johnson, Harvey M. Florman
DOI: 10.1201/9781003148401-11
Cited by: 0

Abstract

The gonadal primordium of a developing organism is the tissue that differentiates into the gonad, where gametes are made. Its future inhabitants – the primordial germ cells – arise at a distant site and so must find their future home in the developing embryo. The primordial germ cells often make a pilgrimage to the gonadal primordium, traveling a dynamic route through changing anatomy by relying on molecular cues to reach and populate the presumptive gonad. Sometimes, however, the gonad is built around the primordial germ cells.

Fields of Study & Subjects

Developmental Biology and Gene Regulation Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities Sperm and Testicular Function

Publication details

Journal / source
CRC Press eBooks
Pages
175–184
Publication date
11 February 2026
Language
EN
Document type
Book chapter