Germline Stem Cells

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Authors: Gary M. Wessel, Julian L. Wong, Carmen J. Williams, Mark A. Johnson, Harvey M. Florman
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Abstract

Germline stem cells are committed to a gametogenic path of differentiation that retain their proliferative capacity. These cells reside in the nascent gonad, where they undergo waves of rapid proliferation punctuated by phases of quiescence in response to hormonal signaling. The lifetime output of gametes is dependent on the germline stem cell population, so depletion of these stem cells results in lower fertility or sterility.

Fields of Study & Subjects

Sperm and Testicular Function Reproductive Biology and Fertility Reproductive biology and impacts on aquatic species

Publication details

Journal / source
CRC Press eBooks
Pages
185–199
Publication date
11 February 2026
Language
EN
Document type
Book chapter